Anti-Cytokeratin, HMW (Hu,Dg,Ca) from Mouse (AE-3) – unconj.
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Overview
SKU RA0386-C.5 Specificity Species Reactivity Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application Flow Cytometry, Immunohistochemistry (frozen sections), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections), Immunoprecipitation, Western Blot
Conjugation Format Intended Use Temperature - Storage Manufacturer / Brand -
Additional Product Information
This antibody recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1), 64kDa (CK3), 59kDa (CK4), 58kDa (CK5), 56kDa (CK6), 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. Clone AE-3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of the basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
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