Anti-Actin, Muscle Specific (Hu,Ms,Rt,Rb,Dg,Ca,Sh,Sw,Mo,Bo,Ck,Ho) from Mouse (HHF35) – unconj.
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Overview
SKU RA0405-C.5 Specificity Species Reactivity Bovine, Cat, Chicken, Dog, Horse, Human, Monkey, Mouse, Rabbit, Rat, Sheep, Swine
Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application Immunofluorescence, Immunohistochemistry (frozen sections), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections), Western Blot
Conjugation Format Intended Use Temperature - Storage Manufacturer / Brand -
Additional Product Information
This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. Anti-muscle specific actin recognizes alpha and gamma isotypes of all muscle groups. Non-muscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of non-muscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative. It stains tumors of smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).
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