Anti-Melanoma & MART-1 & Tyrosinase (Hu) from Mouse (M2-7C10 + M2-9E3 + T311 + HMB45) – unconj.

This antibody cocktail recognizes three melanoma-specific proteins which include MART-1, Tyrosinase, and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T-lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known, but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.