Anti-Phosphotyrosine (all) from Mouse (PTR/793) – unconj.

Protein phosphorylation is a fundamental event in the regulation of a large number of intracellular processes. Phosphorylation of specific tyrosine residues is the result of activation or stimulation of their respective protein tyrosine kinases. The phosphorylated proteins can be auto-phosphorylated kinases or certain cellular protein substrates. Tyrosine-phosphorylated proteins are involved in signal transduction and in the regulation of cell proliferation. An antibody to phosphotyrosine provides an excellent tool for the detection, characterization, and purification of phosphotyrosine-containing proteins. This antibody shows no cross-reaction with other phosphoamino acids and is superb for multiple applications including staining of formalin-fixed, paraffin-embedded tissues.