Anti-p53 tumor suppressor (p53) (Hu) from Mouse (IHC053) – unconj.
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Overview
SKU AB-138372 Specificity Species Reactivity Immunogen Host Species Isotype Clone Clonality (Mono-/Polyclonal) Application ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections), Western Blot
Conjugation Dilution Format < 0.1% NaN3, 1% BSA, concentrate, in Tris buffer (pH 7.3-7.7), ProteinA/G purified antibody
Intended Use Temperature - Storage Temperature - Transport Manufacturer / Brand Uniprot_ID Gene_ID Alias Antigen NY-CO-13, Cellular Tumor Antigen P53, LFS1, Li-Fraumeni Syndrome, P53, P53 Tumor Suppressor, TP53, Transformation related protein 53, TRP53, Tumor Protein, Tumor Protein p53, Tumor Suppressor P53
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Additional Product Information
p53, also known as Tumour Protein 53 or TP53, is a tumour suppressor and transcription factor that functions in a number of anti-cancer activities including DNA repair, cell-cycle arrest, and apoptosis in response to DNA damage or other stressors. Mutations in p53 are linked to a number of malignant tumours, including those of the breast, ovary, bladder, colon, lung, and melanoma. Anti-p53 staining has been used to detect intratubular germ cell neoplasia, and also to distinguish between uterine serous carcinoma and endometrioid carcinoma.
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