dianova constantly develops and validates new antibodies for immunohistochemical (IHC) detection of important biomarkers in formalin-fixed paraffin-embedded (FFPE) tissues.
Under the trademark ONCOdianova new antibodies for tissue-based detection of cancer immunology checkpoint biomarkers are developed, e.g. anti-TIGIT or anti-CD155 and anti-CD73.
(Point-)Mutation-specific antibodies against targets with diagnostic potential, e.g. IDH1 R132H and mutated Calreticulin, are another focus.
Antibodies for preclinical studies in mouse model systems often show suboptimal staining results. Therefore we offer unique antibodies against murine targets. Our anti-msCD31 clone SZ31 is considered as a goldstandard for studies of angiogenesis in mice.
ONCOdianova: IHC-detection of Cancer Immunology Checkpoint markers
dianova develops under the trademark “ONCOdianova” new antibodies for IHC detection of cancer immunology checkpoint biomarkers in (FFPE) tissues, e.g. anti-TIGIT or anti-CD155 and anti-CD73. Our idea is to integrate immunohistochemistry as early as possible in the hybridoma screening procedure.
Tumor (mutation) markers: Validated antibodies for IHC on human tumor tissues
Our premium antibodies (i.a. IDH1 R132H) offer excellent staining features for IHC on formalin-fixed (FFPE) human tissues.
Mouse Pathology: Antibodies for IHC on formalin-fixed and paraffin-embedded (FFPE) tissue of mIce
Our anti-msCD31 antibody clone SZ31 reacts specifically with endothelial cells in vessels and capillaries in mice and is teh best antibody avaliable for IHC-FFPE studies. Here you can find antibodies for further murine CD-Markers as CD3, CD4, CD8 and CD45R.
Antibody Highlights
In this section you can find the respective product sites of our antibody highlights for human and murine FFPE-tissue sections:
- Anti-IDH1 R132H (Hu) from Mouse (clone: H09) FFPE-tissue.
- Anti-TIGIT (Hu) from Mouse (clone: TG1)
- Anti-mutated Calreticulin / CALR (Hu) from Mouse (clone: CAL2) for FFPE-tissue.
- Anti-CD31 (Ms) from Rat (clone: SZ31) for murine FFPE-tissue.
- Anti-CD4 (Ms) from Rat (clone: GHH4) for murine FFPE-tissue.
- Anti-CD8a (Ms) from Rat (clone: GHH8) for murine FFPE-tissue.
- Anti-CD45R (Ms) from Rat (clone: GHH45) for murine FFPE-tissue.
Other Products
In this section you can find higly sensitive and specific monoclonal Epitope tag antibodies (i.a. His-tag) as well as our anti-fibroblast (CD90) antibody.